Client Novo Nordisk Collaborates with Replicate Bioscience to Develop Treatments for Obesity and Diabetes Using Self-Replicating RNA Technology

In The News
August 29, 2025

Ropes & Gray advised Novo Nordisk in a collaboration with Replicate Bioscience to develop treatments using Replicate’s self-replicating RNA (srRNA) novel platform for obesity, type 2 diabetes and other cardiometabolic diseases. The transaction was announced on August 28.

Under the agreement, Novo Nordisk and Replicate will collaborate on certain targets for cardiometabolic diseases. Novo Nordisk will receive a defined, exclusive, worldwide license to use Replicate’s srRNA technology to develop and commercialize the lead programs. Replicate will receive research funding and is eligible to receive up to $550 million. Replicate is also eligible to receive tiered royalties on future product sales as part of the multi-year deal.

The Ropes & Gray team included life sciences licensing partner Hannah England and life sciences licensing associates Ian Nilsen and Ben Ellington.