Ropes & Gray Advised Spyre Therapeutics in $316 Million Public Offering

In The News
October 15, 2025

Ropes & Gray represented Spyre Therapeutics in a $316 million public offering of 17,094,594 shares of its common stock, including the full exercise of the underwriters’ option to purchase up to 2,229,729 additional shares at a public offering price per share of $18.50. The offering priced on October 13, 2025, and closed on October 15, 2025.

Spyre is a clinical-stage biotechnology company advancing best-in-class antibody engineering, dose optimization, and rational therapeutic combinations for the treatment of inflammatory bowel disease and other immune-mediated diseases.

The deal team was led by capital markets partner Tom Danielski and associate Emily Weiss-Cook.